Morphometrical Evaluation of Corpus Callosum Using Mid-Sagittal Brain MRI Images in Patients With Relapsing-Remitting Multiple Sclerosis Referred to Besat Hospital in Hamadan from April 2011 To April 2021; A Retrospective Study

نویسندگان

  • Fatemeh Zohreh-Vand Member of Research Committee, Medical School, Hamadan University of Medical Sciences, Hamadan, Iran.
  • Leili Tapak Department of Biostatistics, School of Health, Hamadan University of Medical Sciences, Hamadan, Iran.
  • Mehrdokht Mazdeh Department of Neurology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
  • Mohammad Bahiraei Department of Radiology, Besat Hospital, Hamadan University of Medical Sciences, Hamadan, Iran.
  • Seyed Kamaledin Hadei Department of Radiology, School of Medicine, Farshchian Cardiovascular Subspecialty Medical Center, Hamadan University of Medical Sciences, Hamadan, Iran.
چکیده مقاله:

Introduction: Corpus callosum (CC) as an intracranial organ is located in midline of cerebrum communicating both right and left hemispheres. CC undergoes morphological changes in multiple sclerosis (MS). Since the morphometrical changes of organs are directly associated with geographical regions, thus the aim of this study was to investigate the morphological alteration of CC in patients with relapsing-remitting MS in Hamadan (Iran) in a retrospective study from April 2011 to April 2021. Materials and Methods: Following conduction of inclusion and exclusion criteria, respectively 54 and 128 Brain MRI images of RRMS patients and healthy individuals were examined morphologically using PmsDICOMViewer software. Two main morphological indices of area (mm2) and longitudinal (mm) parameters were examined in midsagittal sections of Brain MRI images, including the area of CC (ACC) and associated segments, length of CC (LCC) and height of CC (HCC). Finally, the data were analysed by SPSS software (v. 19). P<0.05 was considered as significancy level and data were presented as mean±SEM. Results: Following MS onset, total area of CC (ACC) was decreased significantly (p<0.05) in MS patients than control. Also, the area of rosterum/genu (ARG) and area of anterior half midbody of CC (AAMB) showed significant (p<0.05) incremental and decrimental trends, respectively. In other indices, no significant (p>0.05) differences were detected. Conclusion: Morphometrical measurements of CC are associated with the presence of MS. By the assessment of the anterior half of CC in brain MRI images (ARG and AAMB), the diagnosis of MS can be occurred. Thus, the results of investigation can be proposed as criteria for radiological confirmation of MS diseaese.  

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Frequency of nail involvement in patients referred to the skin clinic of Sina Hospital in Hamadan in April 1999 to April 2000

Background: The nails of hands and feet are involved in the course of many dermatoses and some systemic diseases. They may have diagnostic or prognostic value in some diseases. Objective: The aim of this study was to evaluate nail lesions in patients referred to Dermatology Department of Sina Hospital in Hamadan from April 1999 to April 2000. Patients and Methods: This cross-sectional des...

متن کامل

from linguistics to literature: a linguistic approach to the study of linguistic deviations in the turkish divan of shahriar

chapter i provides an overview of structural linguistics and touches upon the saussurean dichotomies with the final goal of exploring their relevance to the stylistic studies of literature. to provide evidence for the singificance of the study, chapter ii deals with the controversial issue of linguistics and literature, and presents opposing views which, at the same time, have been central to t...

15 صفحه اول

Safety and Efficacy of Fingolimod in Iranian Patients with Relapsing-remitting Multiple Sclerosis

Introduction: Fingolimod is the first confirmed oral immune-modulator to treat Relapsing-Remitting Multiple Sclerosis (RRMS). This study aimed to investigate the safety and efficacy of fingolimod therapy in Iranian patients with RRMS. Methods: In our trial, 50 patients resistant to conventional interferon therapy were assigned to receive fingolimod 0.5 mg per day for 12 months. The number of D...

متن کامل

Corpus callosum function in verbal dichotic listening: inferences from a longitudinal follow-up of Relapsing-Remitting Multiple Sclerosis patients.

This study conducted a follow-up of 13 early-onset slightly disabled Relapsing-Remitting Multiple Sclerosis (RRMS) patients within an year, evaluating both CC area measurements in a midsagittal Magnetic Resonance (MR) image, and Dichotic Listening (DL) testing with stop consonant vowel (C-V) syllables. Patients showed a significant progressive loss of posterior CC areas (isthmus and splenium) r...

متن کامل

A retrospective study of cutaneous fungal infections in patients referred to Imam Reza Hospital of Mashhad, Iran during 2000-2011

Background and Purpose: Detection of agents responsible for cutaneous mycosis may be effective in the prevention of fungal infections from environmental and animal sources. With this background in mind, in this study, we aimed to identify the distribution of cutaneous mycotic infections in patients referred to Imam Reza Hospital of Mashhad, Iran during 2000- 2011. Materials and Methods: In ...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}


عنوان ژورنال

دوره 19  شماره None

صفحات  0- 0

تاریخ انتشار 2022-02

با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.

کلمات کلیدی

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023